ePrints

The Newcastle University research output collection, currently available on ePrints, will shortly be moving to a new open repository platform, Figshare. To prepare for the data migration we have paused adding new content to ePrints, and will resume once the new repository is launched. During this time you will continue to have access to ePrints (but no new content will appear). We will share updates here when available.

Browsing publications by Professor Alastair Hawkins

Newcastle Authors	Title	Year	Full text
Paul Thompson Professor Alastair Hawkins	Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product	2020
Paul Thompson Professor Alastair Hawkins	Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme	2019
Paul Thompson Professor Alastair Hawkins	Synthesis of rigidified shikimic acid derivatives by ring-closing metathesis to imprint inhibitor efficacy against shikimate kinase enzyme	2019
Dr Arnaud Basle Dr Lorraine Hewitt Dr Alan Koh Dr Heather Lamb Paul Thompson et al.	Crystal structure of NucB, a biofilm-degrading endonuclease	2018
Dr Nadia Rostami Professor Alastair Hawkins Dr Richard Holliday Professor Philip Preshaw Professor Nicholas Jakubovics	A Critical Role for Extracellular DNA in Dental Plaque Formation	2017
Paul Thompson Professor Alastair Hawkins	Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study	2017
Dr David Wilkinson Hua Lin Sarah Charlton Dr Adrian Falconer Dr Craig Bullock et al.	The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: Molecular mechanisms and implications for extracellular matrix turnover	2017
Paul Thompson Professor Alastair Hawkins	Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme	2016
Paul Thompson Professor Alastair Hawkins	Frontispiece: Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme	2016
Paul Thompson Professor Alastair Hawkins	Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme	2016
Paul Thompson Professor Alastair Hawkins	Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct	2015