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i-ADHoRe 2.0: An improved tool to detect degenerated genomic homology using genomic profiles

Lookup NU author(s): Dr Cedric Simillion

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Abstract

Summary: i-ADHoRe is a software tool that combines gene content and gene order information of homologous genomic segments into profiles to detect highly degenerated homology relations within and between genomes. The new version offers, besides a significant increase in performance, several optimizations to the algorithm, most importantly to the profile alignment routine. As a result, the annotations of multiple genomes, or parts thereof, can be fed simultaneously into the program, after which it will report all regions of homology, both within and between genomes. © The Author 2007. Published by Oxford University Press. All rights reserved.

Publication metadata

Author(s): Simillion C, Janssens K, Sterck L, Van de peer Y

Publication type: Article

Publication status: Published

Journal: Bioinformatics

Year: 2008

Volume: 24

Issue: 1

Pages: 127-128

ISSN (print): 1367-4803

ISSN (electronic): 1460-2059

Publisher: Oxford University Press

URL: http://dx.doi.org/10.1093/bioinformatics/btm449

DOI: 10.1093/bioinformatics/btm449

PubMed id: 17947255

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