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Macroscopic 2D networks self-assembled from nanometer-sized protein/DNA complexes

Lookup NU author(s): Dr Daniel Frankel, Deqiang Zhou

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Abstract

We demonstrate the self-assembly of DNA and DNA binding proteins into two-dimensional networks that are then addressable by sending a second protein to a specific recognition site on the DNA network. These networks cover centimeters in area but can be addressed with nanometer precision. This hierarchical self-assembly of specific DNA protein complexes will be the basis for complex positioning of single molecules in two and three dimensions. © 2006 American Chemical Society.

Publication metadata

Author(s): Manzanera M, Frankel DJ, Li H, Zhou D, Bruckbauer A, Kreutzmann P, Blackburn JM, Abell C, Rayment T, Klenerman D, Barker PD

Publication type: Article

Publication status: Published

Journal: Nano Letters

Year: 2006

Volume: 6

Issue: 3

Pages: 365-370

ISSN (print): 1530-6984

ISSN (electronic): 1530-6992

URL: http://dx.doi.org/10.1021/nl051599+

DOI: 10.1021/nl051599+

PubMed id: 16522024

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