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The Newcastle University research output collection, currently available on ePrints, will shortly be moving to a new open repository platform, Figshare. To prepare for the data migration we have paused adding new content to ePrints, and will resume once the new repository is launched. During this time you will continue to have access to ePrints (but no new content will appear). We will share updates here when available.

The effect of contrast reduction on pattern-reversal VEPs in suspected multiple sclerosis and optic neuritis

Lookup NU author(s): Dr Keith Mitchell

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Abstract

A retrospective study was conducted to investigate whether the use of low-contrast stimuli in addition to the standard high-contrast stimuli would increase the sensitivity of the pattern-reversal P100 when testing for multiple sclerosis (MS) and optic neuritis (ON). We found that there was a statistically significant increase in the number of abnormal results when using 25′ checks, but not for 50′ checks. Examination of patient records showed that VEP abnormalities to low-contrast stimuli only was not prognostic for subsequent development of multiple sclerosis. © Springer 2005.

Publication metadata

Author(s): Davidson AW, Scott RF, Mitchell KW

Publication type: Article

Publication status: Published

Journal: Documenta Ophthalmologica

Year: 2004

Volume: 109

Issue: 2

Pages: 157-161

ISSN (print): 0012-4486

ISSN (electronic): 1573-2622

Publisher: Springer

URL: http://dx.doi.org/10.1007/s10633-004-3831-9

DOI: 10.1007/s10633-004-3831-9

PubMed id: 15881261

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