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Multiomic Reference Map of Endothelial Mechanosensitive Pathways Under Athero‐ and Erosion‐Prone Flow

Lookup NU author(s): Dr Sara LuzziORCiD, Dr Graham SmithORCiD, Dr Stephen WhiteORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Publication metadata

Author(s): Vidotto G, Luzzi S, Humphries JD, Beal R, McVey D, Nelson CP, Webb TR, Humphries MJ, Smith GR, White SJ

Publication type: Article

Publication status: Published

Journal: Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease

Year: 2026

Volume: 15

Issue: 13

Print publication date: 07/07/2026

Online publication date: 23/06/2026

Acceptance date: 06/04/2026

Date deposited: 18/07/2026

ISSN (electronic): 2047-9980

Publisher: Wiley-Blackwell Publishing, Inc.

URL: https://doi.org/10.1161/JAHA.125.048290

DOI: 10.1161/JAHA.125.048290

Data Access Statement: The combined RNAseq and miRseq data sets are available at GSE300941. Proteomics data are available via ProteomeXchange with identifier PXD075178. In addition, a complete description of the bioinformatic methodology, including scripts for each step including merging miR databases and machine learning are available at https://github.com/GiulioVidotto/Influence_of_miRs_in_regulating_the_response_of_endothelial_cells_to_different_flow_environments

PubMed id: 42333643

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Funding

Funder referenceFunder name
British Heart Foundation [grant: PG/17/67/33218]

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