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Frequency and prognostic significance of genetic abnormalities in a subgroup of intermediate-risk neuroblastoma patients: a SIOPEN study

Lookup NU author(s): Hannah Hartley, Fang Chyi Fong, Dr Al Gabriel, Louise Stevenson, Dr Lisa AllinsonORCiD, Angharad Goodman, Angela Potts, Emily Whittle, Ruby Barford, Dr Katia Mazzocco, Dr Graham SmithORCiD, Adrienne UnsworthORCiD, Michael McCorkindaleORCiD, Nermine Basta, Dr Richard McNallyORCiD, Professor Deborah TweddleORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Publication metadata

Author(s): Hartley HE, Fong FC, Gabriel AS, Stevenson LK, Beckett E, Allinson LM, Goodman A, Potts A, Whittle E, Barford R, Lamparelli A, Herd F, Mazzocco K, Pezzolo A, Morini M, Ardito N, Eva A, Ognibene M, Fischer M, Ackermann S, Rosswog C, Hero B, Smith GR, Unsworth AA, McCorkindale M, George SL, Tall S, Molenaar JJ, Matser Y, Langenberg K, Tytgat G, Noguera R, Berbegall AP, Font-de-Mora J, Combaret V, Pierron G, Muhlethaler-Mottet A, Schoumans J, Tchinda J, Banzola I, Jeison M, Hameiri-Grossman M, Beiske KH, Auger N, Van-Roy N, Basta NO, McNally RJQ, Taschner-Mandl S, Papadakis V, Di-Cataldo A, Wheeler K, Bermudez JD, Beck-Popovic M, Segura V, Canete A, Schleiermacher G, Tweddle DA

Publication type: Article

Publication status: Published

Journal: JCO Precision Oncology

Year: 2026

Volume: 10

Issue: 7

Print publication date: 01/07/2026

Online publication date: 01/07/2026

Acceptance date: 11/03/2026

Date deposited: 13/03/2026

ISSN (electronic): 2473-4284

Publisher: American Society of Clinical Oncology

URL: https://doi.org/10.1200/PO-26-00045

DOI: 10.1200/PO-26-00045

Data Access Statement: The data generated in this study are available within the article and its supplementary data files. The DNA sequencing data generated in this study are available in the European Genome Phenome Archive EGAS50000001908. The RNAseq data have been deposited in Gene Expression Omnibus accession number GSE327331. Any additional data are available upon reasonable request from the corresponding author.

PubMed id: 42385103

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Funding

Funder referenceFunder name
Action Medical Research
Charity Soul
Children’s Cancer North
Great Ormond Street Hospital Children’s Charity (GN 2390)
Little Princess Trust (CCLGA 2018 03 and CCLG 2019 29)
Neuroblastoma UK
Parent donation (The Mohammed family)
SIOPEN
Sir Bobby Robson Foundation
Solving Kids' Cancer UK
The JGW Paterson Foundation

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