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Remodelling of supernumerary leaflet primordia leads to bicuspid aortic valve (BAV) caused by loss of primary cilia

Lookup NU author(s): Dr Ahlam AlqahtaniORCiD, Dr Lorraine EleyORCiD, Cindy Rodrigues Cleto, Leonor Lopez, Dr Chris DerrickORCiD, Mashael Alaradi, Professor Deborah HendersonORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Publication metadata

Author(s): Alqahtani A, Eley L, Newton J, McDonald K, Connolly C, Rodrigues-Cleto C, Neffeova K, Lopez L, Arias J, Derrick CJ, Alaradi M, Kolesova H, Chaudhry B, Henderson DJ

Publication type: Article

Publication status: Published

Journal: Cardiovascular Research

Year: 2025

Volume: 121

Issue: 11

Pages: 1750-1766

Print publication date: 15/09/2025

Online publication date: 11/06/2025

Acceptance date: 09/04/2025

Date deposited: 22/10/2025

ISSN (electronic): 1755-3245

Publisher: Oxford University Press

URL: https://doi.org/10.1093/cvr/cvaf108

DOI: 10.1093/cvr/cvaf108

Data Access Statement: All data that support the findings not presented in main figures and supplementary files are available from the corresponding author upon request.

PubMed id: 40498626

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Funding

Funder referenceFunder name
British Heart Foundation grants (RG/12/15/29935 and RG/19/2/34256)
Czech Science Foundation (24-12330K)
Medical Research Council (MC_PC_21044)

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