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Practical guidance for conducting high-quality and rapid interim analyses in adaptive clinical trials

Lookup NU author(s): Helen MossopORCiD, Zoe WalmsleyORCiD, Dr Nina WilsonORCiD, Dr Opeyemi AgbeleyeORCiD, Michelle Bardgett, Alex Bevin-Nicholls, Dr Matthew Breckons, Mike ColeORCiD, Professor Dawn CraigORCiD, Professor Helen HancockORCiD, Chizoba OparahORCiD, Julia PhillipsonORCiD, Professor Dawn Teare, Dr Katie ThomsonORCiD, Professor James WasonORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Publication metadata

Author(s): Mossop H, Walmsley Z, Wilson N, Agbeleye O, Bardgett M, Bevin-Nicholls A, Breckons M, Cole M, Craig D, Dimairo M, Hancock H, Law M, Lopes A, Noor NM, Oparah C, Pallmann P, Phillipson J, Robertson DS, Teare MD, Thomson KH, Yap C, Wason JMS

Publication type: Article

Publication status: Published

Journal: BMC Medicine

Year: 2025

Volume: 23

Online publication date: 01/10/2025

Acceptance date: 22/08/2025

Date deposited: 01/10/2025

ISSN (electronic): 1741-7015

Publisher: BioMed Central Ltd.

URL: https://doi.org/10.1186/s12916-025-04362-x

DOI: 10.1186/s12916-025-04362-x

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Funding

Funder referenceFunder name
Health and Care Research Wales
National Institute for Health & Care Research (NIHR) CTU Support Funding scheme
NIHR Applied Research Collaboration (ARC) North East and North Cumbria (NENC) (NIHR200173)
NIHR Research Professorship (NIHR301614)

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