Toggle Main Menu Toggle Search

Open Access padlockePrints

The Newcastle University research output collection, currently available on ePrints, will shortly be moving to a new open repository platform, Figshare. To prepare for the data migration we have paused adding new content to ePrints, and will resume once the new repository is launched. During this time you will continue to have access to ePrints (but no new content will appear). We will share updates here when available.

Acute effects of caffeine and taurine co-ingestion on time to exhaustion and thermoregulatory responses to cycling in the heat

Lookup NU author(s): Jess Page, Dr Owen JeffriesORCiD

Downloads

Licence

This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Abstract

Caffeine and taurine are commonly co-ingested pre-exercise but elicit different thermoregulatory responses; however, their combined effect on thermoregulation is unknown. Therefore, we evaluated the effects of oral caffeine and taurine co-ingestion on time to exhaustion (TTE) and thermoregulatory responses to cycling in the heat at the gas exchange threshold (GET). Ten healthy nonheat acclimated participants took part in a double-blind crossover study, completing a TTE in the heat (35°C; 40% relative humidity), cycling at a power output associated with the GET and 1 h after ingesting: caffeine (5 mg/kg) and taurine (50 mg/kg) combined or placebo. Pulmonary gas exchange, core and mean skin temperatures and whole-body sweat rate (WBSR) were recorded throughout. Heat production was determined using partitional calorimetry. There were no differences in TTE between conditions (p = 0.608); however, the rate of oxygen consumption (p = 0.017), minute ventilation (p = 0.029) and heat production (p = 0.019) were higher following the supplement. There were no differences between conditions for skin (p = 0.539) and core temperature (p = 0.699), mean skin blood flow (p = 0.119), respiratory exchange ratio (p = 0.546) and WBSR (p = 0.897). Pre-exercise co-ingestion of caffeine and taurine in the heat had no ergogenic effect despite increasing the ventilatory and metabolic demand. Collectively, these data indicate minimal effects on whole-body thermoregulation.

Publication metadata

Author(s): Aggett J, Page J, Peel J, John K, Matta G, Tallent J, Heffernan S, Jeffries O, Waldron M

Publication type: Article

Publication status: Published

Journal: European Journal of Sport Science

Year: 2025

Volume: 25

Issue: 10

Print publication date: 01/10/2025

Online publication date: 16/09/2025

Acceptance date: 18/08/2025

Date deposited: 10/09/2025

ISSN (print): 1746-1391

ISSN (electronic): 1536-7290

Publisher: John Wiley and Sons Inc

URL: https://doi.org/10.1002/ejsc.70044

DOI: 10.1002/ejsc.70044

Data Access Statement: All data are available upon reasonable request.

Altmetrics

Altmetrics provided by Altmetric

Share