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The Newcastle University research output collection, currently available on ePrints, will shortly be moving to a new open repository platform, Figshare. To prepare for the data migration we have paused adding new content to ePrints, and will resume once the new repository is launched. During this time you will continue to have access to ePrints (but no new content will appear). We will share updates here when available.

Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia

Lookup NU author(s): Dr Kate HarrisORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Publication metadata

Author(s): Cogswell TJ, Josa-Cullere L, Zimmer D, Galan SRG, Jay-Smith M, Harris KS, Bataille CJR, Jackson TR, Zhang D, Davies SG, Vyas P, Milne TA, Wynne GM, Russell AJ

Publication type: Article

Publication status: Published

Journal: RSC Medicinal Chemistry

Year: 2024

Volume: 15

Issue: 10

Pages: 3495-3506

Print publication date: 01/10/2024

Online publication date: 22/07/2024

Acceptance date: 14/07/2024

Date deposited: 05/04/2025

ISSN (electronic): 2632-8682

Publisher: Royal Society of Chemistry

URL: https://doi.org/10.1039/D4MD00275J

DOI: 10.1039/D4MD00275J

Data Access Statement: The data supporting this article have been included as part of the ESI.

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Funding

Funder referenceFunder name
OxStem Ltd

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