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Mild Uncoupling of Mitochondria Synergistically Enhances Senolytic Specificity and Sensitivity of BH3 Mimetics

Lookup NU author(s): Dr Edward FielderORCiD, Abbas Ishaq, Evon Low, Joseph Laws, Aisha Calista, Dr Jemma CastleORCiD, Professor Thomas von Zglinicki, Dr Satomi MiwaORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Publication metadata

Author(s): Fielder EP, Ishaq A, Low E, Laws JA, Calista A, Castle J, von Zglinicki T, Miwa S

Publication type: Article

Publication status: Published

Journal: Aging Biology

Year: 2024

Volume: 2

Online publication date: 20/02/2024

Acceptance date: 11/02/2024

Date deposited: 07/02/2025

ISSN (electronic): 2994-2578

Publisher: Aging Biology, LLC

URL: https://doi.org/10.59368/agingbio.20240022

DOI: 10.59368/agingbio.20240022

Data Access Statement: Datasets related to this article can be found at https://data. mendeley.com/datasets/2chc5kgx7y/1, an open-source online data repository hosted at Mendeley Data.

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Funding

Funder referenceFunder name
Cancer Research UK Pioneer Award C12161/A24009, BBSRC Grant No. BB/S006710/1
H2020 WIDESPREAD Project 857524
UK SPINE Proof of Concept—Bridge Program

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