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Neurotoxicology: A clinical systems-based review

Lookup NU author(s): Professor Peter Blain

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Abstract

© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. Neurological disease caused by toxins is widespread but under-recognised. Despite increasing public interest and a growing number of novel potential neurotoxins, diagnosis of neurotoxic disease is often delayed or missed, resulting in poorer patient outcomes. This article discusses neurotoxic syndromes using a systems-based approach, focusing on environmental and occupational agents. We do not discuss recreational drugs, pharmaceutical agents or developmental neurotoxins in detail. We aim to provide neurologists with a working understanding of the scenarios in which a clinical presentation may be due to a neurotoxin and how to approach confirmation of the diagnosis.

Publication metadata

Author(s): Vonberg FW, Blain PG

Publication type: Review

Publication status: Published

Journal: Practical Neurology

Year: 2024

Volume: 24

Issue: 5

Pages: 357-368

Print publication date: 01/10/2024

Online publication date: 07/06/2024

Acceptance date: 12/05/2024

ISSN (print): 1474-7758

ISSN (electronic): 1474-7766

Publisher: BMJ Publishing Group

URL: https://doi.org/10.1136/pn-2023-003983

DOI: 10.1136/pn-2023-003983

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