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Lipoprotein(a) testing in lipid clinics across the UK: Results of a national survey

Lookup NU author(s): Dr R Neely

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).

Abstract

© 2024. Lipoprotein(a) is an independent risk factor for cardiovascular disease and its use is recommended in national and international guidelines for cardiovascular disease risk stratification. We undertook a survey to understand the availability and application of lipoprotein(a) measurement across UK lipid clinics. Fifty-three out of an estimated 200 lipid clinics (27%) provided responses. 81% of fifty-three clinics had access to lipoprotein(a) measurement. 27 clinics disclosed the number of lipoprotein(a) tests ordered annually with approximately half of the clinics (52%) requesting 0-250 tests per year. 60% measured lipoprotein(a) once per patient and the leading indication was a personal or family history of premature history of cardiovascular disease in those <60 years old. 63% of clinics that provided comments with lipoprotein(a) results graded cardiovascular risk as per the HEART UK consensus statement. 60% of clinics performed family cascade testing on lipoprotein(a) results ≥200nmol/L. Lipoprotein(a) was reported in nmol/L, mg/dL or mg/L by 48%, 24% and 28% of responding clinics, respectively. National effort is required to provide universal access to Lipoprotein(a) measurement and to harmonise the clinical application of this data.

Publication metadata

Author(s): Ansari S, Neely RDG, Payne J, Cegla J

Publication type: Article

Publication status: Published

Journal: Journal of Clinical Lipidology

Year: 2024

Volume: 18

Issue: 3

Pages: e477-e481

Print publication date: 01/05/2024

Online publication date: 15/02/2024

Acceptance date: 09/02/2024

Date deposited: 17/04/2025

ISSN (print): 1933-2874

ISSN (electronic): 1876-4789

Publisher: Elsevier Ltd

URL: https://doi.org/10.1016/j.jacl.2024.02.004

DOI: 10.1016/j.jacl.2024.02.004

PubMed id: 38418291

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