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Reduced binding of apoE4 to complement factor H promotes amyloid‐β oligomerization and neuroinflammation

Lookup NU author(s): Kitty Crompton, Dr Adam WollmanORCiD

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Author(s): Chernyaeva L, Ratti G, Teirilä L, Fudo S, Rankka U, Pelkonen A, Korhonen P, Leskinen K, Keskitalo S, Salokas K, Gkolfinopoulou C, Crompton K, Javanainen M, Happonen L, Varjosalo M, Malm T, Leinonen V, Chroni A, Saavalainen P, Meri S, Kajander T, Wollman A, Nissilä E, Haapasalo K

Publication type: Article

Publication status: Published

Journal: EMBO Reports

Year: 2023

Volume: 24

Issue: 7

Print publication date: 05/07/2023

Online publication date: 08/05/2023

Acceptance date: 24/04/2023

Date deposited: 13/03/2024

ISSN (print): 1469-221X

ISSN (electronic): 1469-3178

Publisher: Wiley-Blackwell Publishing Ltd

URL: https://doi.org/10.15252/embr.202256467

DOI: 10.15252/embr.202256467

Data Access Statement: mRNA data: Gene Expression Omnibus GSE193513 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE193513). Proteomic data: MassIVE MSV000088618 (https://massive.ucsd.edu/ProteoSAFe/dataset.jsp?task=595bf56584824151bb0b73e81f3caa73). MS crosslinking data: (http://massive.ucsd.edu/ProteoSAFe/status.jsp?task=40074352d93d41e8859034cc2f677bb0). Molecular dynamics data: (DOI:https://doi.org/10.5281/zenodo.7533587. Link: https://doi.org/10.5281/zenodo.7533587).

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