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Lookup NU author(s): Melvin JoyORCiD
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
Objective: The objective of this study was to evaluate the antimicrobial activity of methanolic extract of Ludwigia parviflora L. using standard bacterial strains and compare its activity with that of standard antibiotics. Methods: The antibacterial activity and antibiotic susceptibility tests were done by disk diffusion method using MTCC bacterial strains. Results: The study revealed that the methanolic extract of the whole plant of L. parviflora L. was effective to inhibit the growth of Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli. Among the tested strains, S. aureus, P. aeruginosa, K. pneumoniae, and E. coli were more susceptible to the methanolic extract of L. parviflora than the commonly using antibiotic tetracycline 30 mcg. The activity of methanolic extract was also higher than the activity of gentamicin 10 mcg against the P. aeruginosa. Conclusion: The study concluded that the crude methanolic extract of the whole plant of L. parviflora L. is a good source for antibacterial agent against S. aureus, P. aeruginosa, K. pneumoniae, and E. coli. Hence, this plant can be used as a natural alternative to the common antibiotics such as gentamicin and tetracycline against common bacterial infections after validating its pharmacological and toxicological activities.
Author(s): George S, Joy M
Publication type: Article
Publication status: Published
Journal: Asian Journal of Pharmaceutical and Clinical Research
Year: 2019
Volume: 12
Issue: 3
Pages: 430-432
Print publication date: 07/03/2019
Acceptance date: 19/01/2019
Date deposited: 02/04/2026
ISSN (print): 0974-2441
ISSN (electronic): 2455-3891
Publisher: Innovare Academic Sciences Pvt. Ltd
URL: https://doi.org/10.22159/ajpcr.2019.v12i3.30818
DOI: 10.22159/ajpcr.2019.v12i3.30818
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