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National survey on caffeine use in neonatal units across the United Kingdom

Lookup NU author(s): Dr Vrinda Nair, Dr Prakash Kannan Loganathan

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Abstract

© 2022 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd. Aim: To understand the variations in practice for caffeine use among neonatal units in the United Kingdom. Methods: An online survey was sent to every neonatal unit in the United Kingdom. Results: We received a response from 92 neonatal units (47%) with the proportion of response from special care, Local neonatal units, neonatal intensive care units and neonatal surgical units were 23%, 34%, 23% and 21% respectively. All the units reported the use of caffeine, and 40 units (46%) initiated caffeine within 24 h of birth. Fifty-nine units (64%) reported routine use of caffeine for pre-term infants <32 weeks. Seventy-one units (77%) reported that they continue caffeine for infants needing mechanical ventilation. Thirty-one units (34%) discontinued caffeine at 34 weeks post-menstrual age, irrespective of the respiratory support. Ten units (11%) reported discontinuation of caffeine only after weaning off all respiratory support, and 40% of units had a variable practice of discontinuing caffeine depending on the individual baby. Seventy-nine units (86%) reported they would regularly optimise caffeine dose based on weight checks. Conclusion: Our survey showed some variation in practice with regards to the timing of caffeine initiation, gestational age cut-off for routine caffeine prescription and discontinuation.

Publication metadata

Author(s): Grainge S, Nair V, Kannan Loganathan P

Publication type: Article

Publication status: Published

Journal: Acta Paediatrica

Year: 2023

Volume: 112

Issue: 9

Pages: 1865-1869

Print publication date: 01/09/2023

Online publication date: 18/12/2022

Acceptance date: 15/12/2022

ISSN (print): 0803-5253

ISSN (electronic): 1651-2227

Publisher: John Wiley and Sons Inc.

URL: https://doi.org/10.1111/apa.16635

DOI: 10.1111/apa.16635

PubMed id: 36529520

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