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Graves' disease: Moving forwards

Lookup NU author(s): Dr Laura Lane, Dr Claire WoodORCiD, Professor Timothy CheethamORCiD

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Abstract

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. Graves' disease is a rare disorder that continues to present clinicians and families with a series of challenges. There are no new established treatments for children or adolescents, but the outcomes of recent clinical trials and meta-analyses have helped clinicians to prepare families for the road ahead. We have a more refined understanding of how to administer antithyroid drugs, which one to use and how long to treat the young person. We also have a greater insight into how best to reduce any risks associated with surgery and radioiodine. We understand more about long-term outcomes and their determinants and have greater awareness about the impact of the disease and its treatment on quality of life. A holistic approach to management is key to supporting and counselling young people and their families about the diagnosis and management options. In this review, we will discuss the recent literature and reflect on how this should be translated into clinical practice.

Publication metadata

Author(s): Lane LC, Wood CL, Cheetham T

Publication type: Review

Publication status: Published

Journal: Archives of Disease in Childhood

Year: 2023

Volume: 108

Issue: 4

Pages: 276-281

Print publication date: 01/04/2023

Online publication date: 13/07/2022

Acceptance date: 27/06/2022

ISSN (print): 0003-9888

ISSN (electronic): 1468-2044

Publisher: BMJ Publishing Group

URL: https://doi.org/10.1136/archdischild-2022-323905

DOI: 10.1136/archdischild-2022-323905

PubMed id: 35831126

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