Toggle Main Menu Toggle Search

Open Access padlockePrints

The Newcastle University research output collection, currently available on ePrints, will shortly be moving to a new open repository platform, Figshare. To prepare for the data migration we have paused adding new content to ePrints, and will resume once the new repository is launched. During this time you will continue to have access to ePrints (but no new content will appear). We will share updates here when available.

Clinical outcomes of percutaneous coronary intervention in high-risk patients turned down for surgical revascularization

Lookup NU author(s): Dr Ayman Al-atta, Dr Mohammad Alkhalil, Dr Mohaned Egred

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.

Abstract

© 2022 Wiley Periodicals LLC. Aims: There are limited data on outcomes of PCI in surgical turndown patientsespecially in those presenting with ACS. Methods and Results: A retrospective analysis of prospectively collected data of patients who were turned down for CABG and had PCI between 2013 and 2020. All consecutive patients (449), ACS (n = 245) and no-ACS (n = 204) were included. In-hospital complications occurred in 28 patients (6.2%). At 30 days, 27 patients (6.0%) died (18 patients in the ACS group [7.3%] vs. 9 patients in the no-ACS group [4.4%], p = 0.23). Following multivariate analysis, no significant difference in long-term mortality was observed between the two groups (median follow-up of 4 [2–6] years, hazard ratio [HR]: 1.08, 95% confidence interval [CI]: 0.75–1.58, p = 0.667). In propensity score-matched analysis, the adjusted mortality risk was also not different between the groups (HR: 0.74, 95% CI: 0.25–1.26, p = 0.374). Independent predictors of mortality included chronic kidney disease stage ≥ 3 (HR: 1.64, 95% CI: 1.13–2.39, p = 0.009), high European System for Cardiac Operative Risk Evaluation II (HR: 1.02, 95% CI: 1.00–1.05, p = 0.035), and laser atherectomy use (HR: 3.35, 95% CI: 1.32–8.54, p = 0.011). Conclusions: PCI in surgical patients turndown patients appears safe. ACSpresentation was associated with more comorbid illnesses; however, afteradjustment, ACS did not independently confer additional risk of mortality.

Publication metadata

Author(s): Farag M, Al-Atta A, Abdalazeem I, Salim T, Alkhalil M, Egred M

Publication type: Article

Publication status: Published

Journal: Catheterization and Cardiovascular Interventions

Year: 2022

Volume: 100

Issue: 3

Pages: 360-366

Print publication date: 01/09/2022

Online publication date: 01/07/2022

Acceptance date: 11/06/2022

ISSN (print): 1522-1946

ISSN (electronic): 1522-726X

Publisher: John Wiley and Sons Inc.

URL: https://doi.org/10.1002/ccd.30318

DOI: 10.1002/ccd.30318

Altmetrics

Altmetrics provided by Altmetric

Share