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Dynamical task switching in cellular computers

Lookup NU author(s): Dr Angel Goni-Moreno

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Licence

This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Abstract

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. We present a scheme for implementing a version of task switching in engineered bacteria, based on the manipulation of plasmid copy numbers. Our method allows for the embedding of multiple computations in a cellular population, whilst minimising resource usage inefficiency. We describe the results of computational simulations of our model, and discuss the potential for future work in this area.

Publication metadata

Author(s): Goni-Moreno A, de la Cruz F, Rodriguez-Paton A, Amos M

Publication type: Article

Publication status: Published

Journal: Life

Year: 2019

Volume: 9

Issue: 1

Online publication date: 26/01/2019

Acceptance date: 23/01/2019

Date deposited: 11/03/2019

ISSN (electronic): 2075-1729

Publisher: MDPI AG

URL: https://doi.org/10.3390/life9010014

DOI: 10.3390/life9010014

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Funding

Funder referenceFunder name
BFU2017-86378-P
B2017/BMD-3691
EU-H2020-BIOTEC-820699
UK-EPSRC-EP/R019002/1

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