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Applying the Airbrakes: Treating Mitochondrial Disease with Hypoxia

Lookup NU author(s): Dr Oliver RussellORCiD, Emeritus Professor Robert Lightowlers, Emeritus Professor Doug Turnbull

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Abstract

A paper from Jain et al. (2016) using whole-genome CRISPR knockout libraries in human cells and models of mitochondrial disease suggests chronic hypoxia could be an unexpected treatment for disorders of mitochondrial respiration.

Publication metadata

Author(s): Russell OM, Lightowlers RN, Turnbull DM

Publication type: Editorial

Publication status: Published

Journal: Molecular Cell

Year: 2016

Volume: 62

Issue: 1

Pages: 5-6

Online publication date: 07/04/2016

Acceptance date: 01/01/1900

ISSN (print): 1097-2765

ISSN (electronic): 1097-4164

Publisher: Cell Press

URL: http://dx.doi.org/10.1016/j.molcel.2016.03.027

DOI: 10.1016/j.molcel.2016.03.027

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