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Resting state fMRI brain network connectivity in dementia with Lewy bodies and Alzheimer's disease

Lookup NU author(s): Dr Luis Peraza RodriguezORCiD, Professor Marcus Kaiser, Dr Michael FirbankORCiD, Dr Sara Graziadio, Professor John-Paul TaylorORCiD

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).

Abstract

Dementia with Lewy bodies (DLB) is the second to third most common cause of neurodegenerative dementia after Alzheimer’s disease (AD). It is characterised by cognitive fluctuations, visual hallucinations, and Parkinsonism. However at early stages, both diseases can present similar clinical phenotypes which obstruct differential diagnosis and proper treatment.In this study, we analysed resting state fMRI (rs-fMRI) images from AD and DLB patients as well as healthy controls using graph theory. The use of network analysis to the study of DLB revealed significant differences with AD and healthy controls

Publication metadata

Author(s): Peraza LR, Kaiser M, Firbank M, Graziadio S, O'Brien J, Taylor J-P

Editor(s): Organization for Human Brain Mapping, OHBM

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: 20th Annual Meeting of the Organization for Human Brain Mapping (OHBM 2014)

Year of Conference: 2014

Date deposited: 15/06/2014

Publisher: Organization for Human Brain Mapping

URL: http://www.humanbrainmapping.org/i4a/pages/index.cfm?pageID=3565

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