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Recurrence of Wegener's granulomatosis with de novo intraoral presentation treated successfully with rituximab

Lookup NU author(s): Dr Konrad Staines, Dr Bernard Higgins

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Abstract

We describe a unique case of a recurrence of Wegener's granulomatosis (WG) that presented with oral pain involving a left maxillary molar, which thereafter led to an extraction. Oral lesions with a classical appearance of strawberry gingivitis developed following the extraction. The primary disease did not have any oral manifestations. Both the primary disease and recurrence responded to rituximab, a monoclonal B-cell depleting antibody. Rituximab is emerging as a drug with significant potential to improve treatment of primary and, as described in this case, recurrent WG. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 108: 76-80)

Publication metadata

Author(s): Staines KS, Higgins B

Publication type: Article

Publication status: Published

Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology

Year: 2009

Volume: 108

Issue: 1

Pages: 76-80

ISSN (print): 1079-2104

ISSN (electronic): 1528-395X

Publisher: Mosby, Inc.

URL: http://dx.doi.org/10.1016/j.tripleo.2009.02.025

DOI: 10.1016/j.tripleo.2009.02.025

Notes: Northern Oral Medicine Group (UK) Annual Meeting, Liverpool, UK,

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