Toggle Main Menu Toggle Search

Open Access padlockePrints

The Newcastle University research output collection, currently available on ePrints, will shortly be moving to a new open repository platform, Figshare. To prepare for the data migration we have paused adding new content to ePrints, and will resume once the new repository is launched. During this time you will continue to have access to ePrints (but no new content will appear). We will share updates here when available.

Growth inhibitory substances in human breast cyst fluid

Lookup NU author(s): Professor Thomas Lennard

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.

Abstract

Women who have breast cysts with intracystic Na/K < 3 may have a higher risk of breast cancer than those with intracystic Na/K > 3. Low/undetectable concentrations of TNFalpha and IL-4, both of which have been shown to inhibit growth of human breast cancer cell lines, were found in the majority of breast cyst fluid samples. Intracystic oestradiol concentrations were significantly higher in the low electrolyte ratio group than in the high electrolyte ratio group. Imbalance between growth stimulatory and growth inhibitory substances in cystic breast disease may be an explanation for the higher risk of breast cancer particularly in the low electrolyte ratio group.

Publication metadata

Author(s): Lai LC, Chan CTM, Cornell C, Lennard TWJ

Publication type: Article

Publication status: Unknown

Journal: Anticancer Research

Year: 1993

Volume: 13

Issue: 1

Pages: 225-228

Print publication date: 01/01/1993

ISSN (print): 0250-7005

ISSN (electronic):

Share